Phenidone , 98.5% , 92-43-3

Synonym(s):
Phenidone

CAS NO.：92-43-3

Empirical Formula: C9H10N2O

Molecular Weight: 162.19

MDL number: MFCD00003094

EINECS: 202-155-1

PRODUCT Properties

• Melting point: 119-121 °C(lit.)
• Boiling point: 288.88°C (rough estimate)
• Density: 1.1436 (rough estimate)
• vapor pressure: 0.002Pa at 25℃
• refractive index: 1.5600 (estimate)
• storage temp.: Sealed in dry,Room Temperature
• solubility: methanol: 0.1 g/mL, clear
• form: White to off-white solid.
• pka: 9.50±0.30(Predicted)
• color: White to Light yellow to Light orange
• Water Solubility: SOLUBLE IN HOT WATER
• Merck: 14,7309
• BRN: 131856
• Stability: Stable, but light sensitive. Incompatible with strong acids, strong oxidizing agents, strong bases.
• LogP: 0.119 at 25℃
• CAS DataBase Reference: 92-43-3(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-3-pyrazolidinone(92-43-3)
• EPA Substance Registry System: 3-Pyrazolidinone, 1-phenyl- (92-43-3)

Description and Uses

Phenidone inhibits both the LO (lipoxygenase) and Cox (cyclooxygenase) pathways, the synthesis of Fos-related antigen protein, and is described as an anti-inflammatory and anti-oxidant compound. Phenidone has been shown to block neurotoxicity induced by kainate, and weakens oxidative stress induced by lipopolysaccharide.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H302-H411
• Precautionary statements: P264-P270-P273-P301+P312-P391-P501
• Hazard Codes: Xn,N
• Risk Statements: 22-51/53
• Safety Statements: 61
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 2
• RTECS: UQ8750000
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29331990
• Toxicity: LD50 orl-rat: 200 mg/kg KODAK* -,-,71