Home Categories API Palmatine
A6704112

Palmatine , 97% , 3486-67-7

CAS NO.:3486-67-7

Empirical Formula: C21H22NO4+

Molecular Weight: 352.4

MDL number: MFCD00221758

Pack Size Price Stock Quantity
5G RMB175.20 In Stock
25G RMB623.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 205°C
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Powder
color  Yellow
LogP -1.120 (est)

Description and Uses

This quaternary alkaloid occurs frequently in the Rhoeadales, being found in Cop tis japonica Mak. (Ranunculaceae); Berberis heteropoda Schrenk; B. vulgaris L. (Berberidaceae); Coscinium blumeatum Miers; Fibrauria chloroleuca Miers;Jatrorrhiza palmata (Lam.) Miers. (Menispermaceae); and Phellodendron amurense Rupr. (Rutcaeae). The base is usually obtained as the iodide dihydrate forming orange-yellow needles from H20, m.p. 241°C (dec.). Other salts that have been prepared include the chloride, green-yellow needles from H20, m.p. 205°C (dec.); nitrate, yellow needles, from H20, m.p. 239°C (dec.); perchlorate, m.p. 262°C (dec.); sulphate, m.p. 250°C; platinichloride, m.p. 236°C and the thiocyanate, m.p. 210°C (dec.). The alkaloid resembles berberine in yielding addition compounds with CHCl3 and Me2CO. On catalytic hydrogenation it gives tetrahydropalmatine, while on oxidation with alkaline KMn04 it furnishes corydaldine and hemipinic acid.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280
Toxicity mouse,LD50,subcutaneous,135mg/kg (135mg/kg),Russian Pharmacology and Toxicology Vol. 31, Pg. 129, 1968.

RELATED PRODUCTS