Octenidine Dihydrochloride , ≥98.0%(HPLC) , 70775-75-6

CAS NO.：70775-75-6

Empirical Formula: C36H64Cl2N4

Molecular Weight: 623.826

MDL number: MFCD01938808

EINECS: 274-861-8

PRODUCT Properties

• Melting point: 215-217℃
• Density: 1.046[at 20℃]
• vapor pressure: 0Pa at 25℃
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Soluble in dimethyl sulfoxide and methanol.
• form: Solid
• color: White to Off-White
• Water Solubility: 14.2g/L at 20℃
• Merck: 14,6754
• Stability: Hygroscopic
• InChIKey: SMGTYJPMKXNQFY-UHFFFAOYSA-N
• SMILES: [N+]1(CCCCCCCCCC[N+]2C=CC(NCCCCCCCC)=CC=2)=CC=C(NCCCCCCCC)C=C1.[Cl-].[Cl-]
• LogP: 1.5 at 23℃

Description and Uses

The antiseptic agent octenidine dihydrochloride (OCT) was developed by Sterling Winthrop (WIN41464-2) in the 1980s as an alternative to the anti-plaque agent CHX and successfully tested in vitro and in vivo. OCT has a broad spectrum of activity with similar effectiveness against Gram-negative and Gram-positive bacteria, fungi, and yeasts. Moreover, it has been shown that it may effectively interfere with the co-aggregation of dental plaque microbial colonizers without disturbing the normal, healthy oral flora. In a standardized comparison of antimicrobial activity ofthe antiseptic agents triclosan, polyvinylpyrrolidone-iodine, OCT, polyhexamethylene biguanide, and Chlorhexidine digluconat (CHX) using the min-imal effective concentration and minimum bactericidal con-centration, OCT was the most effective active agent of alltested antimicrobial substances. In other studies, the antibacterial and antiplaque efficacy of OCT was equal to or even greater than that of CHX[1].

Octenidine is an antiseptic (topical). Octenidine is a cationic surfactant and bis-(dihydropyridinyl)-decane derivative.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302+H312+H332-H315-H319-H335
• Precautionary statements: P280-P301+P312-P362+P364
• HS Code: 2933399990