Home Categories Biochemical Engineering 5′-O-(4,4′-Dimethoxytrityl)thymidine
A6535912

5′-O-(4,4′-Dimethoxytrityl)thymidine , 98% , 40615-39-2

Synonym(s):
DMT-T

CAS NO.:40615-39-2

Empirical Formula: C31H32N2O7

Molecular Weight: 544.59

MDL number: MFCD00010113

EINECS: 255-003-1

Pack Size Price Stock Quantity
1G RMB57.60 In Stock
5G RMB119.20 In Stock
25G RMB408.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 114-116 °C (subl.)(lit.)
Boiling point: 618.41°C (rough estimate)
Density  1.2483 (rough estimate)
vapor pressure  0Pa at 20℃
refractive index  7 ° (C=1, MeOH)
storage temp.  2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
pka 9.55±0.10(Predicted)
form  Powder
color  White to off-white
Water Solubility  3mg/L at 20℃
BRN  599297
Stability: Store in Freezer
LogP 4.61 at 20℃
CAS DataBase Reference 40615-39-2(CAS DataBase Reference)
EPA Substance Registry System Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- (40615-39-2)

Description and Uses

5'-O-(4,4'-Dimethoxytrityl)thymidine is used in the solid-phase synthesis of polynucleotides and polythymidylic acids by the block coupling phosphotriester method. Further, it is used in the stereoselective synthesis of 3'-deoxy-3'-threo-hydroxymethyl nucleoside. In addition to this, it is used as a research tool for antiviral and anticancer studies.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H413
Precautionary statements  P273
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
1-3-10
Hazard Note  Irritant
HS Code  29349990

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