A6478825
Tris-Hydrochloride Buffer , 1M,pH7.4 , 77-86-1
Synonym(s):
Tris;Tromethamine;Tris base;Trometamol;Tris(Hydroxymethyl)aminomethane
CAS NO.：77-86-1
Empirical Formula: C4H11NO3
Molecular Weight: 121.14
MDL number: MFCD00004679
EINECS: 201-064-4
| Pack Size | Price | Stock | Quantity |
| 400ml | RMB271.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 167-172 °C(lit.) |
| Boiling point: | 219-220 °C10 mm Hg(lit.) |
| Density | 1,353 g/cm3 |
| vapor pressure | 0.0267 hPa (20 °C) |
| refractive index | 1.4170 (estimate) |
| Flash point: | 219-220°C/10mm |
| storage temp. | 20-25°C |
| solubility | H2O: 4 M at 20 °C, clear, colorless |
| form | crystalline |
| color | white |
| PH Range | 7 - 9 |
| PH | 10.5-12.0(4 m in water, 25 °C) |
| pka | 8.1(at 25℃) |
| Water Solubility | 550 g/L (25 ºC) |
| λmax | λ: 260 nm Amax: 0.10 λ: 280 nm Amax: 0.08 |
| Sensitive | Hygroscopic |
| Merck | 14,9772 |
| BRN | 741883 |
| Stability: | Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture. |
| InChIKey | LENZDBCJOHFCAS-UHFFFAOYSA-N |
| LogP | -2.515 (est) |
| CAS DataBase Reference | 77-86-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1) |
| EPA Substance Registry System | Tris(hydroxymethyl)aminomethane (77-86-1) |
Description and Uses
tromethamine can help mask odor in a formulation. It is also used as a buffer, keeping product pH stable.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39-24/25-23 |
| WGK Germany | 2 |
| RTECS | TY2900000 |
| F | 3 |
| TSCA | Yes |
| HazardClass | IRRITANT |
| HS Code | 29221980 |
| Hazardous Substances Data | 77-86-1(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rat > 5000 mg/kg |
