<i>N</i>-Methylisatoic Anhydride , 98% , 10328-92-4

Synonym(s):
1-Methyl-1H -benzo[d ][1,3]oxazine-2,4-dione;1-Methyl-4H -3,1-benzoxazine-2,4(1H )dione

CAS NO.：10328-92-4

Empirical Formula: C9H7NO3

Molecular Weight: 177.16

MDL number: MFCD00006815

EINECS: 233-714-8

PRODUCT Properties

• Melting point: 165 °C (dec.)(lit.)
• Boiling point: 309.06°C (rough estimate)
• Density: 1.3312 (rough estimate)
• vapor density: 6.1 (vs air)
• refractive index: 1.5200 (estimate)
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Soluble in DMSO
• form: Solid
• pka: -2.24±0.20(Predicted)
• color: White to yellow
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 10328-92-4(CAS DataBase Reference)
• EPA Substance Registry System: 2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl- (10328-92-4)

Description and Uses

N-Methylisatoic anhydride is a 2'-OH selective acylation agent of RNAs, and is widely used for resolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• RTECS: DM3140000
• TSCA: Yes
• HS Code: 2934.99.4400