Home Categories Organic Chemistry 4-Nitrophenylboronic Acid (contains varying amounts of Anhydride)
A6245512

4-Nitrophenylboronic Acid (contains varying amounts of Anhydride) , ≥95.0% , 24067-17-2

Synonym(s):
p-nitro-benzeneboronic acid;p-Nitrophenylboronic acid;4-Nitrobenzeneboronic acid

CAS NO.:24067-17-2

Empirical Formula: C6H6BNO4

Molecular Weight: 166.93

MDL number: MFCD00161360

EINECS: 627-647-7

Pack Size Price Stock Quantity
1G RMB39.20 In Stock
5G RMB183.20 In Stock
25G RMB764.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 285-290°C (dec.)
Boiling point: 373.7±44.0 °C(Predicted)
Density  1.40±0.1 g/cm3(Predicted)
storage temp.  Inert atmosphere,Room Temperature
solubility  DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 15 mg/ml; Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
pka 7.04±0.10(Predicted)
form  Crystalline Powder
color  White to yellow
Water Solubility  Slightly soluble in water.
InChIKey NSFJAFZHYOAMHL-UHFFFAOYSA-N
CAS DataBase Reference 24067-17-2(CAS DataBase Reference)

Description and Uses

4-Nitrobenzeneboronic acid is an arylboronic acid building block that has been used in the synthesis of phenols.

Reagent used for

  • Ligand-free palladium-catalyzed Suzuki-Miyaura cross-couplings
  • Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines
  • Diels-Alder or C-H activation reactions
  • Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulations
  • N-arylation of phenylurea using copper acetylacetonate catalyst
  • Environmentally benign one-pot synthesis through a double arylation process
  • Copper-mediated cyanations
  • copper-catalyzed arylations
  • Regioselective glycosylations
  • Suzuki couplings followed by arylations
  • X-ray absorption on rhodium-grafted hydrotalcite catalyst for heterogeneous 1,4-addition reaction of organoboron reagents to electron deficient olefins

Reagent used in Preparation of
  • Combretastatin analogs as potential antitumor agents
  • Human immunodeficiency virus (HIV) protease inhibitors with antiviral activities against drug-resistant viruses

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H302
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  22
Safety Statements  26-36/37/39-24/25
WGK Germany  3
Hazard Note  Harmful
HS Code  29319090

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