N-octanoyl-D-erythro-sphingosine , >99% , 74713-59-0
Pack Size | Price | Stock | Quantity |
5MG | RMB1279.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 68-70°C |
Boiling point: | 541.37°C (rough estimate) |
Density | 0.9974 (rough estimate) |
refractive index | 1.6000 (estimate) |
storage temp. | −20°C |
solubility | DMSO or ethanol: soluble |
form | waxy solid |
color | White |
Stability: | Temperature Sensitive |
CAS DataBase Reference | 74713-59-0(CAS DataBase Reference) |
Description and Uses
C8-ceramide (74713-59-0) is a cell permeable ceramide analog. Stimulates ceramide-activated protein kinase.1?Induces apoptosis.2?Reported to inhibit apoptosis and gap junction intercellular communication (GJIC) in rat liver epithelial cells.3?C8-ceramide induces the secretion of brain-derived neurotrophic factor (BDNF) from microglia?in vitro.4
A biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-2 secretion and induces apoptosis
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H332-H335 |
Precautionary statements | P261-P280-P305+P351+P338 |
Safety Statements | 24/25 |
WGK Germany | 3 |
HS Code | 29225000 |