Home Categories API Naftifine hydrochloride
A6203912

Naftifine hydrochloride , 99% , 65473-14-5

CAS NO.:65473-14-5

Empirical Formula: C21H22ClN

Molecular Weight: 323.86

MDL number: MFCD00059047

EINECS: 620-502-9

Pack Size Price Stock Quantity
1G RMB327.20 In Stock
5G RMB524.00 In Stock
25G RMB3999.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 172-175°C
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  ethanol: soluble50mg/mL
form  Solid
color  White to Off-White
Merck  14,6355
InChI InChI=1S/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20;/h2-15H,16-17H2,1H3;1H/b11-8+;
InChIKey OLUNPKFOFGZHRT-YGCVIUNWSA-N
SMILES N(C/C=C/C1=CC=CC=C1)(C)CC1=C2C(C=CC=C2)=CC=C1.[H]Cl
CAS DataBase Reference 65473-14-5(CAS DataBase Reference)

Description and Uses

Naftifine hydrochloride is a topical antifungal agent which acts via inhibiting squalene epoxidase. It demonstrates good activity against Trichophyton, Epidermophyton, Microsporum, Aspergillus, and species. It is the prototype of a significantly improved series of antifungal agents, exemplified by SF 86-327 in which the phenyl group of naftifine has been replaced by t-butylace tylene.

Antimycotic allylamine. An antifungal (topical) agent.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
WGK Germany  nwg
RTECS  QJ8650000
HS Code  29214990

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