A6203912
Naftifine hydrochloride , 99% , 65473-14-5
CAS NO.:65473-14-5
Empirical Formula: C21H22ClN
Molecular Weight: 323.86
MDL number: MFCD00059047
EINECS: 620-502-9
Pack Size | Price | Stock | Quantity |
1G | RMB327.20 | In Stock |
|
5G | RMB524.00 | In Stock |
|
25G | RMB3999.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 172-175°C |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | ethanol: soluble50mg/mL |
form | Solid |
color | White to Off-White |
Merck | 14,6355 |
InChI | InChI=1S/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20;/h2-15H,16-17H2,1H3;1H/b11-8+; |
InChIKey | OLUNPKFOFGZHRT-YGCVIUNWSA-N |
SMILES | N(C/C=C/C1=CC=CC=C1)(C)CC1=C2C(C=CC=C2)=CC=C1.[H]Cl |
CAS DataBase Reference | 65473-14-5(CAS DataBase Reference) |
Description and Uses
Naftifine hydrochloride is a topical antifungal agent which acts via inhibiting squalene epoxidase. It demonstrates good activity against Trichophyton, Epidermophyton, Microsporum, Aspergillus, and species. It is the prototype of a significantly improved series of antifungal agents, exemplified by SF 86-327 in which the phenyl group of naftifine has been replaced by t-butylace tylene.
Antimycotic allylamine. An antifungal (topical) agent.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319 |
Precautionary statements | P261-P305+P351+P338 |
Safety Statements | 24/25 |
WGK Germany | nwg |
RTECS | QJ8650000 |
HS Code | 29214990 |