Naringin , 95% , 10236-47-2

Synonym(s):
4′,5,7-Trihydroxyflavanone 7-rhamnoglucoside;Naringenin 7-neohesperidoside;Naringenine-7-rhamnosidoglucoside;Naringoside

CAS NO.：10236-47-2

Empirical Formula: C27H32O14

Molecular Weight: 580.53

MDL number: MFCD00148888

EINECS: 233-566-4

PRODUCT Properties

• Melting point: 166 °C
• alpha: -91 º (c=1, C2H5OH)
• Boiling point: 559.35°C (rough estimate)
• Density: 1.3285 (rough estimate)
• vapor pressure: 2.25Pa at 20℃
• FEMA: 2769 | NARINGEN EXTRACT (CITRUS PARADISI MACF.)
• refractive index: -84 ° (C=2, EtOH)
• storage temp.: 2-8°C
• solubility: DMSO : 1 mg/mL (1.72 mM; Need ultrasonic)H2O : 1 mg/mL (1.72 mM; ultrasonic and warming and heat to 80°C)
• form: crystalline
• pka: 7.17±0.40(Predicted)
• color: off-white
• optical activity: [α]20/D 80±10°, c = 1% in ethanol
• Water Solubility: Soluble in water, alcohol, acetone and warm acetic acid.
• Merck: 14,6425
• BRN: 102012
• LogP: -0.44 at 20℃
• CAS DataBase Reference: 10236-47-2(CAS DataBase Reference)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)- (10236-47-2)

Description and Uses

Naringin is also called naringoside, hesperidin, and isohesperidin. It is a pale yellow flavanone compound extracted from immature or nearly mature outer layer of C. paradisi Macfad which belongs to Citrus grandis (L.) Osbeck. It tastes bitter and is naturally existed in the skin and flesh of Rutaceae like grapefruit, mandarin orange, and orange. It is also one of the active ingredients in many traditional Chinese medi cines like Rhizoma Drynariae, Immature Bitter Orange, Fructus Aurantii, and Exocarpium Citri Grandis. The contents of naringin in different plants vary greatly with the category and origin, and the content of naringin is high in immature fruits . In terms of traditional Chinese medicine, the flavor of grapefruit is sweet and sour, and the nature is cold; the flavors of its peel are sweet, pungent, and bitter, and the nature of its peel is warm. Both the pulp and the peel of grapefruit have the bio logical function including reducing phlegm, helping digestion, relieving abdominal distention, and fast diaphragm. And they are mainly used for the treatment of cough with asthma, sense of suppression in the chest, coldness and pain in abdomen, dys peptic retention, and hernia.

antihaemorrhagic, antiinflammatory

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• RTECS: QN6340000
• F: 3
• TSCA: Yes
• HS Code: 29389090