A6147312
3-Nitrophenol , standardforGC,>99%(GC) , 554-84-7
Synonym(s):
m-Nitrophenol;m-NP;3-Nitrophenol;3-NP;m-Nitrophenol
CAS NO.：554-84-7
Empirical Formula: C6H5NO3
Molecular Weight: 139.11
MDL number: MFCD00007240
EINECS: 209-073-5
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 96-98 °C (lit.) |
| Boiling point: | 194 °C/70 mmHg (lit.) |
| Density | 1,49 g/cm3 |
| refractive index | 1.5723 (estimate) |
| Flash point: | 102°C |
| storage temp. | Store at +5°C to +30°C. |
| solubility | 13.5g/l insoluble |
| pka | 8.28(at 25℃) |
| form | Crystalline Powder |
| color | Yellow to brown |
| PH | 6.6-8.6 (H2O, 20℃) |
| PH Range | 6.6(colourless)-8.6(yellow/orange) |
| Water Solubility | 13.5 g/L (25 ºC) |
| λmax | 570nm |
| Merck | 14,6618 |
| BRN | 1907946 |
| Major Application | Display device, semiconductor device, sensors, high voltage capacitors, energetic materials, electrolyte batteries, inks, correction fluid, detergent, leak detection method, lubricants, insecticide, food storage, inhibition of amyloidoses, detect bacterialinfection, drugs, material for evaluating dental caries activity |
| InChIKey | RTZZCYNQPHTPPL-UHFFFAOYSA-N |
| CAS DataBase Reference | 554-84-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 3-nitro-(554-84-7) |
| EPA Substance Registry System | m-Nitrophenol (554-84-7) |
Description and Uses
3-Nitrophenol is a chemical reagent used in various organic syntheses. Used in the synthesis of RAGE inhibitors via the etherification of phenols. Also used in the synthesis of kinase inhibitors against epidermal growth factor receptor T790M mutation.
Safety
| Symbol(GHS) |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302-H315-H318 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-38-41-36/37/38-33-20/21/22 |
| Safety Statements | 26-36/37-45-36/37/39-22-28 |
| RIDADR | UN 1663 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | SM1925000 |
| F | 8 |
| Autoignition Temperature | 400 °C |
| Hazard Note | Harmful/Irritant |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29089000 |
| Hazardous Substances Data | 554-84-7(Hazardous Substances Data) |
| Toxicity | LD50 orally in mice, rats: 1414, 933 mg/kg, K. C. Back et al., Reclassification of Materials Listed as Transportation Health Hazards (TSA-20-72-3; PB214-270, 1972) |
