Home Categories Organic Chemistry Methyl Diethylphosphonoacetate
A5654912

Methyl Diethylphosphonoacetate , >96.0%(GC) , 1067-74-9

Synonym(s):
(Methoxycarbonylmethyl) diethoxyphosphine oxide;[(Methoxycarbonyl)methyl]phosphonic acid diethyl ester;Methyl P,P-diethylphosphonoacetate;NSC 147757

CAS NO.:1067-74-9

Empirical Formula: C7H15O5P

Molecular Weight: 210.16

MDL number: MFCD00009081

EINECS: 213-938-2

Pack Size Price Stock Quantity
5G RMB25.60 In Stock
25G RMB37.60 In Stock
100G RMB105.60 In Stock
500G RMB502.40 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Boiling point: 127-131 °C9 mm Hg(lit.)
Density  1.145 g/mL at 25 °C(lit.)
refractive index  n20/D 1.433(lit.)
Flash point: >230 °F
storage temp.  Sealed in dry,Room Temperature
solubility  Miscible with tetrahydrofuran.
form  Liquid
color  Clear colorless to faint yellow
BRN  1782397
InChI InChI=1S/C7H15O5P/c1-4-11-13(9,12-5-2)6-7(8)10-3/h4-6H2,1-3H3
InChIKey CTSAXXHOGZNKJR-UHFFFAOYSA-N
SMILES C(OC)(=O)CP(OCC)(OCC)=O

Description and Uses

Methyl diethylphosphonoacetate is used as a reagent in the preparation of allylic fluorides compounds and in regioselective Diels-Alder reactions. It also serves as a reactant in the preparation of substituted thiophenes and furans, which finds application in type 2 diabetes treatment. Further, it acts as a precursor in the synthesis of pyridone alkaloids and immunosuppressive cyclopentanediol derivatives. In addition to this, it is utilized in the modification of botulinum neurotoxin serotype A protease inhibitors.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
10
HS Code  29310095

RELATED PRODUCTS