2-Methyl-1,3-propanediol , 98% , 2163-42-0

Synonym(s):
1,3-Dihydroxy-2-methylpropane;2-Methylpropan-1,3-diol;Methylpropanediol

CAS NO.：2163-42-0

Empirical Formula: C4H10O2

Molecular Weight: 90.12

MDL number: MFCD00082586

EINECS: 412-350-5

PRODUCT Properties

• Melting point: -91 °C (lit.)
• Boiling point: 123-125 °C/20 mmHg (lit.)
• Density: 1.015 g/mL at 25 °C (lit.)
• vapor density: 3.2 (vs air)
• refractive index: n20/D 1.445(lit.)
• Flash point: >230 °F
• storage temp.: Sealed in dry,Room Temperature
• solubility: Chloroform (Soluble), DMSO (Slightly), Methanol (Slightly)
• form: Oil
• pka: 14.51±0.10(Predicted)
• color: Colourless
• Odor: little to no odor
• BRN: 1731422
• InChIKey: QWGRWMMWNDWRQN-UHFFFAOYSA-N
• LogP: -0.740 (est)

Description and Uses

2-Methyl-1,3-propanediol, MPD, is produced by Arco with an estimated capacity of about 7000 t/a. The process is designed for the production of 1,4-butanediol as an alternative to Reppe technology and the acetoxylation of butadiene. The raw material propylene oxide is isomerized to allyl alcohol in the fifirst step. Hydroformylation of allyl alcohol gives 4- hydroxybutanal (79 %) and 3-hydroxy-2-methylpropanal (11 %). The last step comprises hydrogenation of the n and iso intermediates to the corresponding diols.

β-Hydroxyisobutanol is used as a reagent in the synthesis of pyrazolo[1,5-a]pyridinecarbonyl-substituted spirocyclic piperidine ketals as inhibitors of HCV protein NS4B and of hepatitis C viral replication and their lack of cytotoxicity in human cells.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H319-H315-H335
• Precautionary statements: P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
• Risk Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 1
• HS Code: 2905.39.9000