Home Categories Chemical Reagents Methyl D-(+)-Lactate
A5538912

Methyl D-(+)-Lactate , ≥98.0%(GC) , 17392-83-5

Synonym(s):
D-Lactic acid methyl ester;Methyl (R)-(+)-lactate

CAS NO.:17392-83-5

Empirical Formula: C4H8O3

Molecular Weight: 104.1

MDL number: MFCD00004517

EINECS: 241-420-6

Pack Size Price Stock Quantity
5G RMB23.20 In Stock
25G RMB31.20 In Stock
100G RMB51.20 In Stock
500G RMB158.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

alpha  8.5 º (c=neat)
Boiling point: 144-145 °C(lit.)
Density  1.09 g/mL at 25 °C(lit.)
refractive index  n20/D 1.413(lit.)
Flash point: 121 °F
storage temp.  Inert atmosphere,2-8°C
solubility  Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)
form  Liquid
pka 13.07±0.20(Predicted)
color  Clear colorless
optical activity [α]21/D +8.4°, neat
Water Solubility  miscible, hydrolyses
Merck  14,6094
InChIKey LPEKGGXMPWTOCB-GSVOUGTGSA-N
LogP -0.719 (est)

Description and Uses

(+)-Methyl D-lactate can be used as a starting material in the asymmetric preparation of:

  • Neomethymycin, a macrolide which contains 12-membered macrolactone that is used as a potent biological agent.
  • PM-toxin A.

It can also be used as a chiral pool along with D-(-)-tartaric acid in the stereoselective total synthesis of separacenes A and B via Trost-Rychnovsky alkyne rearrangement, Horner-Wadsworth-Emmons olefination as well as Corey-Bakshi-Shibata reaction.

Safety

Symbol(GHS) 
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H319-H335
Precautionary statements  P210-P305+P351+P338
Hazard Codes  Xi
Risk Statements  10-36/37
Safety Statements  16-24-24/25
RIDADR  UN 3272 3/PG 3
WGK Germany  1
HazardClass  3
PackingGroup  III
HS Code  29181100

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