3-Maleimidopropionic acid N-hydroxysuccinimide ester , 99% , 55750-62-4
Synonym(s):
BMPS;N-Succinimidyl 3-maleimidopropionate;N-(3-Maleimidopropionyloxy)succinimide;N-Maleoyl-β-alanine N′-hydroxysuccinimide ester;N-(3-Maleimidopropionyloxy)succinimide
CAS NO.:55750-62-4
Empirical Formula: C11H10N2O6
Molecular Weight: 266.21
MDL number: MFCD00043141
EINECS: 627-755-4
Pack Size | Price | Stock | Quantity |
250MG | RMB48.80 | In Stock |
|
1G | RMB66.40 | In Stock |
|
5G | RMB297.60 | In Stock |
|
25g | RMB1409.60 | In Stock |
|
100g | RMB5126.40 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 168-170 °C(lit.) |
Boiling point: | 448.8±47.0 °C(Predicted) |
Density | 1.55±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,2-8°C |
solubility | Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) |
pka | -2.39±0.20(Predicted) |
form | Solid |
color | White to Light Brown |
Water Solubility | Insoluble in water. |
Sensitive | Moisture Sensitive |
BRN | 1492578 |
InChI | InChI=1S/C11H10N2O6/c14-7-1-2-8(15)12(7)6-5-11(18)19-13-9(16)3-4-10(13)17/h1-2H,3-6H2 |
InChIKey | JKHVDAUOODACDU-UHFFFAOYSA-N |
SMILES | N1(CCC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O |
CAS DataBase Reference | 55750-62-4(CAS DataBase Reference) |
Description and Uses
3-Maleimido-propionic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.