α-MaleiMidopropionyl-ω-succiniMidyl-8(ethylene glycol) , 95% , 756525-93-6

Synonym(s):
31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic acid 2,5-dioxo-1-pyrrolidinyl ester;31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic acid 2,5-dioxo-1-pyrrolidinyl ester;Maleimide PEG8 succinimidyl ester;Maleimide-PEG₈-NHS ester;Maleimide-PEG8-NHS ester

CAS NO.：756525-93-6

Empirical Formula: C30H47N3O15

Molecular Weight: 689.71

MDL number: MFCD11041144

PRODUCT Properties

• Density: 1.30±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: DMSO : ≥ 100 mg/mL (144.99 mM)
• pka: 15.01±0.46(Predicted)
• form: powder
• color: Light yellowish

Description and Uses

Mal-amido-PEG8-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Heterobifunctional crosslinker with an ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 39.2 angstroms.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
• WGK Germany: 3
• HS Code: 2928009090