Home Categories Maleimide-PEG<sub>2</sub>-succinimidyl ester
A5494412

Maleimide-PEG<sub>2</sub>-succinimidyl ester , 99% , 955094-26-5

Synonym(s):
3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid 2,5-dioxo-1-pyrrolidinyl ester;Maleimide-PEG2-NHS

CAS NO.:955094-26-5

Empirical Formula: C18H23N3O9

Molecular Weight: 425.39

MDL number: MFCD11041137

Pack Size Price Stock Quantity
50MG RMB567.20 In Stock
100MG RMB979.20 In Stock
250MG RMB2159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 90.0 to 94.0 °C
Density  1.41±0.1 g/cm3(Predicted)
storage temp.  -20°C
form  powder to crystal
pka 15.00±0.46(Predicted)
color  White to Light yellow
InChI InChI=1S/C18H23N3O9/c22-13(5-8-20-14(23)1-2-15(20)24)19-7-10-29-12-11-28-9-6-18(27)30-21-16(25)3-4-17(21)26/h1-2H,3-12H2,(H,19,22)
InChIKey TZPDZOJURBVWHS-UHFFFAOYSA-N
SMILES C(ON1C(=O)CCC1=O)(=O)CCOCCOCCNC(=O)CCN1C(=O)C=CC1=O

Description and Uses

Mal-amido-PEG2-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Maleimide-PEG2-NHS Ester(955094-26-5) is a heterobifunctional crosslinker with short ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 17.6 angstroms.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  3
HS Code  29280000

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