α-MaleiMidopropionyl-ω-succiniMidyl-6(ethylene glycol) , 96% , 1137109-21-7

Synonym(s):
25-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azapentacosanoic acid 2,5-dioxo-1-pyrrolidinyl ester;Maleimide-PEG₆-NHS ester

CAS NO.：1137109-21-7

Empirical Formula: C26H39N3O13

Molecular Weight: 601.6

MDL number: MFCD11041093

PRODUCT Properties

• Melting point: 54 - 57°C
• Density: 1.32±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: Acetonitrile (Slightly), Water (Slightly)
• pka: 15.01±0.46(Predicted)
• form: Solid
• color: White to Off-White

Description and Uses

Mal-amido-PEG6-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Heterobifunctional crosslinker with an ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 31.7 angstroms.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P280-P302+P352-P362+P364
• WGK Germany: 3
• HS Code: 2928009090