A1362612
Boc-15-amino-4,7,10,13-tetraoxapentadecanoic acid , 97% , 756525-91-4
| Pack Size | Price | Stock | Quantity |
| 100MG | RMB180.80 | In Stock |
|
| 500MG | RMB1423.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 504.5±50.0 °C(Predicted) |
| Density | 1.124±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | 2-8°C |
| form | Oil |
| pka | 4.28±0.10(Predicted) |
| color | Colorless to light yellow |
| λmax | 254nm(lit.) |
| InChI | InChI=1S/C16H31NO8/c1-16(2,3)25-15(20)17-5-7-22-9-11-24-13-12-23-10-8-21-6-4-14(18)19/h4-13H2,1-3H3,(H,17,20)(H,18,19) |
| InChIKey | YCEYBRZRNOJORY-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCC(O)=O |
Description and Uses
t-Boc-N-amido-PEG4-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid is used as a substitution variant of cocaine esterase with improved stability and its use in treatment of cocaine overdose.
Safety
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29225090 |
