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A5457556

ProClin8020preservatives , 122-99-6

Synonym(s):
PHE;2-Phenoxyethanol;PhG;Ethylene glycol monophenyl ether;DOWANOL EPh

CAS NO.:122-99-6

Empirical Formula: C8H10O2

Molecular Weight: 138.16

MDL number: MFCD00046644

EINECS: 204-589-7

Pack Size Price Stock Quantity
400ml RMB255.20 In Stock
1l RMB511.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 11-13 °C (lit.)
Boiling point: 247 °C (lit.)
Density  1.102 g/mL at 25 °C (lit.)
vapor density  4.8 (vs air)
vapor pressure  0.01 mm Hg ( 20 °C)
FEMA  4620 | 2-PHENOXYETHANOL
refractive index  n20/D 1.539
Flash point: >230 °F
storage temp.  Store below +30°C.
solubility  soluble, clear, colorless to very faintly yellow
pka 14.36±0.10(Predicted)
form  Liquid
Specific Gravity 1.109 (20/4℃)
color  Clear colorless
PH 7 (10g/l, H2O, 23℃)
Odor Faint aromatic odor
PH Range 7 at 10 g/l at 23 °C
explosive limit 1.4-9.0%(V)
Odor Type floral
Water Solubility  30 g/L (20 ºC)
Merck  14,7257
BRN  1364011
InChIKey QCDWFXQBSFUVSP-UHFFFAOYSA-N
LogP 1.2 at 23℃

Description and Uses

Phenoxyethanol is an organic chemical compound, a glycol ether often used in dermatological products such as skin creams and sunscreen. It is a colorless oily liquid. It is a bactericide (usually used in conjunction with quaternary ammonium compounds). Phenoxyethanol is used in many applications such as cosmetics, vaccines and pharmaceuticals as a preservative.

Phenoxyethanol is a preservative used in consumer and health care products, including vaccines, pen inks, ear drops, shampoos, skin cleansers, moisturizers, sun care products, and topical medicaments. The preservative Euxyl-K 400 also contains 2-phenoxyethanol, in combination with methyldibromoglutaronitrile.
Phenoxyethanol is commonly used in cosmetics for its antibacterial and antifungal properties. It is increasingly being used in vaccines as a substitute for thiomersal and is also a component of pen inks and, more rarely, ear drops.Reactions to phenoxyethanol have rarely been reported. Three cases of CoU induced by phenoxyethanol in cosmetics have been reported.2-Phenoxyethanol is used as a single agent and in combination with other preservatives such as 1,2-dibromo-2,4-dicyanobutane (Euxyl K 400) and parabens, or in conjunction with quaternary ammonium compounds.The possibility of immunological IgE-mediated reaction could not be confirmed because specific IgE against 2-phenoxyethanol was negative.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
Hazard Codes  Xn,Xi
Risk Statements  22-36-R36-R22
Safety Statements  26-S26
WGK Germany  1
RTECS  KM0350000
Autoignition Temperature 535 °C DIN 51794
Hazard Note  Irritant
TSCA  Yes
HS Code  29094990
Toxicity LD50 orally in Rabbit: 1850 mg/kg LD50 dermal Rabbit > 2000 mg/kg

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