α-Melanocyte stimulating hormone , ≥97%(HPLC) , 581-05-5
Synonym(s):
α-Melanocyte-Stimulating Hormone;α-Melanotropin;α-MSH;α-MSH, Melanotropin
CAS NO.：581-05-5
Empirical Formula: C77H109N21O19S
Molecular Weight: 1664.88
MDL number: MFCD00133062
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB758.40 | In Stock |
|
| 25MG | RMB2145.60 | In Stock |
|
| 100mg | RMB5318.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Density | 1.48±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | insoluble in EtOH; ≥10.44 mg/mL in H2O with ultrasonic; ≥166.5 mg/mL in DMSO with gentle warming |
| pka | 4.43±0.10(Predicted) |
| form | Lyophilized |
| color | White to off-white |
| Water Solubility | Soluble in water (~1 mg/ml). |
| BRN | 741840 |
Description and Uses
A pituitary hormone secreted from the pars intermedia, MSH was one of the first adenohypophysial hormones demonstrated to be present in vertebrates, from jawless fish to mammals, together with adrenocorticotropic hormone (ACTH). The fact that MSH is derived from a precursor protein called proopiomelanocortin (POMC) was demonstrated in 1979, using the pars intermedia from the bovine pituitary.
alpha-Melanocyte Stimulating Hormone amide is an endogenous melanocortin receptor agonist (Ki values are 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively). Anti-inflammatory peptide; antagonizes proinflammatory mediators, including TNF-α, IL-6 and NO and induces anti-inflammatory cytokine IL-10. Inhibits food intake and induces penile erections following i.c.v. administration.
Safety
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
