Minocycline hydrochloride , 98% , 13614-98-7

Synonym(s):
7-Dimethylamino-6-demethyl-6-deoxytetracycline, HCl;Minocycline hydrochloride;Minocycline, Hydrochloride - CAS 13614-98-7 - Calbiochem;Minomycin

CAS NO.：13614-98-7

Empirical Formula: C23H28ClN3O7

Molecular Weight: 493.94

MDL number: MFCD00083669

EINECS: 237-099-7

Pack Size	Price	Stock	Quantity
250MG	RMB35.20	In Stock
1G	RMB80.00	In Stock
5G	RMB292.00	In Stock
25g	RMB1015.20	In Stock
100g	RMB3538.40	In Stock
others			Enquire

Update time: 2022-07-08

PRODUCT Properties

Melting point:	205-210° (dec)
Boiling point:	813℃
Flash point:	>110°(230°F)
storage temp.	2-8°C
solubility	Sparingly soluble in water, slightly soluble in ethanol (96 per cent). It dissolves in solutions of alkali hydroxides and carbonates.
form	crystalline
color	yellow
Water Solubility	Freely soluble in water
Merck	14,6202
Stability:	Light Sensitive
InChIKey	GLMUAFMGXXHGLU-VQAITOIOSA-N
SMILES	[C@@]12([H])C[C@@]3([H])C(C(=O)C4C(O)=CC=C(N(C)C)C=4C3)=C(O)[C@]1(O)C(=O)C(C(=O)N)=C(O)[C@H]2N(C)C.Cl \|&1:0,3,21,31,r\|
LogP	0.808 (est)

Description and Uses

Minocycline HCl (13614-98-7) displays antiapoptotic, anti-inflammatory1 activity. Prevents neuropathic pain in a rat sciatic nerve injury model.1 Reduces MMP-9 activity.2 Attenuates disease severity in mouse models of multiple sclerosis.3 Displays neuroprotective activity.4 Minocycline HCl may be effective in methotrexate-induced lung fibrosis.5?Orally active and brain penetrant.

antiinflammatory

Safety

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H317-H360-H362-H303-H315-H319-H335
Precautionary statements	P201-P202-P260-P263-P264-P270-P272-P280-P302+P352+P333+P313+P363-P308+P313-P405-P501-P261-P280a-P304+P340-P305+P351+P338-P501a
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	3249
WGK Germany	3
RTECS	QI7630500
HazardClass	6.1(b)
PackingGroup	III
HS Code	29413020
Toxicity	human,TDLo,oral,14286ug/kg/10 (14.286mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTIONLUNGS, THORAX, OR RESPIRATION: DYSPNEASKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE",Archives of Internal Medicine. Vol. 154, Pg. 1633, 1994.