Licochalcone A , ≥96% , 58749-22-7

Synonym(s):
(E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one;(E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one;4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone;Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem

CAS NO.：58749-22-7

Empirical Formula: C21H22O4

Molecular Weight: 338.4

MDL number: MFCD01417903

EINECS: 635-678-2

PRODUCT Properties

• Melting point: 100°
• Boiling point: 532.6±50.0 °C(Predicted)
• Density: 1.171±0.06 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM); DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM); Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM)
• pka: 7.82±0.15(Predicted)
• form: Yellow solid
• color: Yellow-orange
• BRN: 4534154
• InChIKey: KAZSKMJFUPEHHW-DHZHZOJOSA-N

Description and Uses

Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302+H312+H332
• Precautionary statements: P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
• Hazard Codes: Xn
• Risk Statements: 20/21/22
• Safety Statements: 36/37
• WGK Germany: 3
• RTECS: UB8755000