Kaempferitrin<img src="/content/dam/sigma-aldrich/head/search/new.png" alt="New" /> , 97%(NMR) , 482-38-2

CAS NO.：482-38-2

Empirical Formula: C27H30O14

Molecular Weight: 578.52

MDL number:

PRODUCT Properties

• Melting point: 202～203℃
• Boiling point: 908.6±65.0 °C(Predicted)
• Density: 1.70
• storage temp.: -20°C
• solubility: DMSO : 125 mg/mL (216.07 mM; Need ultrasonic)
• form: powder
• pka: 5.81±0.40(Predicted)
• color: white to beige
• Stability: Hygroscopic

Description and Uses

Kaempferitrin is a flavonoid glycoside that has been found in B. pinnatum and has diverse biological activities. It scavenges DPPH radicals (IC₅₀ = 8.73 μg/ml) and is active against the bacteria S. aureus, P. aeruginosa, and S. typhi, as well as the fungi C. albicans, C. parapsilosis, and C. neoformans (MICs = 16-32 μg/ml). Kaempferitrin inhibits LPS-and IFN-γ-induced nitric oxide (NO) production in isolated mouse macrophages (IC₅₀ = 40 μM). It decreases blood glucose levels in a rat model of alloxan-induced diabetes when administered at a dose of 100 mg/kg.

Kaempferitirin is a glycoside of Kaempferol (K100000), a plant flavonoid that exhibits antioxidant properties and is known to reduce risks of various types cancer and cardiovascular diseases. Kaempferitirin have been isolated as natural products from plants such as Hedyotis Verticilata.

Safety

• Symbol(GHS): GHS07,GHS02
• Signal word: Warning
• Hazard statements: H302+H312+H332-H315-H319-H228
• Precautionary statements: P501-P261-P270-P240-P210-P241-P271-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
• Safety Statements: 24/25
• HS Code: 29389090