one-component solvent for volumetric Karl Fischer titration(methanol-free titrating agent) , Water ≤0.01%, used as a reaction medium , 109-86-4
Synonym(s):
Water;1-Pentanol;2-Methoxyethanol;Ethylene glycol monomethyl ether;Methyl glycol
CAS NO.：109-86-4
Empirical Formula: C3H8O2
Molecular Weight: 76.09
MDL number: MFCD00081734
EINECS: 231-791-2
PRODUCT Properties
| Melting point: | -85 °C |
| Boiling point: | 124-125 °C(lit.) |
| Density | 0.965 g/mL at 25 °C(lit.) |
| vapor density | 2.62 (vs air) |
| vapor pressure | 6.17 mm Hg ( 20 °C) |
| refractive index | n |
| Flash point: | 115 °F |
| storage temp. | Store at +5°C to +30°C. |
| solubility | Very soluble in acetone, dimethylsulfoxide, and 95% ethanol (quoted, Keith and Walters, 1992). Miscible with N,N-dimethylformamide, ether, and glycerol (Windholz et al., 1983). |
| pka | 15.7(at 25℃) |
| form | Liquid |
| color | green cap |
| Relative polarity | 1 |
| PH Range | 5- 7 at 25 °C |
| Odor | Mild ethereal. |
| explosive limit | 2.5-20%(V) |
| Water Solubility | SOLUBLE |
| λmax | λ: 213 nm Amax: 1.00 λ: 240 nm Amax: 0.20 λ: 260 nm Amax: 0.05 λ: 300-400 nm Amax: 0.01 |
| Merck | 14,6038 |
| BRN | 1731074 |
| Henry's Law Constant | (x 10-2 atm?m3/mol):
4.41, 3.63, 11.6, 3.09, and 3.813 at 10, 15, 20, 25, and 30 °C, respectively (EPICS, Ashworth et
al., 1988) |
| Exposure limits | TLV-TWA skin 5 ppm (15.5 mg/m3)
(ACGIH), 25 ppm (77.5 mg/m3) (OSHA). |
| Dielectric constant | 15.8（20℃） |
| Stability: | Stable, but contact with air may lead to the formation of explosive peroxides. A peroxide test should be carried out before this material is used if it has been exposed to air for some time, especially if it is to be purified by distillation. Contact with strong oxidizing agents may cause fire or explosion. Incompatible with strong bases, ac |
| InChIKey | XNWFRZJHXBZDAG-UHFFFAOYSA-N |
| LogP | -0.77 at 20℃ |
Description and Uses
2-Methoxyethanol (2-ME), also known as methoxyethanol or ethylene glycol monomethyl ether, is a glycol ether that has been known since the 1920s, but its use significantly increased in the 1970s. Cellosolve was a solvent product containing glycol ethers and registered in the 1920s by Carbide and Carbon Chemicals Corp. Glycol ethers are derived from either ethylene oxide (E-series) or propylene oxide (p-series) combined with an alcohol. Methoxyethanol is an E-series glycol ether derived from methanol and ethylene oxide. Other commonly used glycol ethers include ethoxyethanol, butoxyethanol, and methoxypropanol. Use of methoxyethanol has declined in recent years due to risk management procedures and replacement by other substances.
2-Methoxyethanol is considered a non-comedogenic raw material. It is used as a solvent in nail products and as a stabilizer in cosmetic emulsions. It is able to penetrate the skin and may cause skin irritation.
Safety
| Symbol(GHS) |    GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H226-H302+H312+H332-H360FD-H370-H373 |
| Precautionary statements | P210-P280-P301+P312-P303+P361+P353-P304+P340+P312-P308+P311 |
| Hazard Codes | T,F,C |
| Risk Statements | 60-61-10-20/21/22-39/23/24/25-23/24/25-11-35-34-36/38 |
| Safety Statements | 53-45-36/37-16-26-23-36/37/39 |
| RIDADR | UN 1188 3/PG 3 |
| OEB | C |
| OEL | TWA: 0.1 ppm (0.3 mg/m3) [skin] |
| WGK Germany | 3 |
| RTECS | ZC0110000 |
| F | 10 |
| Autoignition Temperature | 548 °F |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29332990 |
| Toxicity | LD50 in rats, guinea pigs (mg/kg): 2460, 950 orally (Smyth); LC50 (7 hr in air) in mice: 4.6 mg/l (Werner) |
| IDLA | 200 ppm |
