Home Categories Pharmaceutical intermediates isoquinolin-6-amine
A5177112

isoquinolin-6-amine , 97% , 23687-26-5

CAS NO.:23687-26-5

Empirical Formula: C9H8N2

Molecular Weight: 144.17

MDL number: MFCD04114862

EINECS: 639-440-9

Pack Size Price Stock Quantity
250mg RMB88.80 In Stock
1G RMB135.20 In Stock
5g RMB520.00 In Stock
10g RMB879.20 In Stock
25g RMB1839.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 211-212 °C(Solv: benzene (71-43-2))
Boiling point: 343.1±15.0 °C(Predicted)
Density  1.210±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  DMF (Slightly), DMSO (Sparingly), Methanol (Slightly)
form  solid
pka 7.10±0.10(Predicted)
color  Light yellow to yellow

Description and Uses

6-Aminoisoquinoline is an organosynthetic intermediate used in the preparation of Netarsudil, which is a drug used in the treatment and management of glaucoma and high intraocular pressure.

6-Aminoisoquinoline is a reactant used in the preparation of N-[{2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)-pyridin-3-yl}methyl] N''-(6,6-fused heterocyclic) ureas as highly potent TRPV1 antagonists.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P271-P261
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
HS Code  2933499090

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