Home Categories Biochemical Engineering <I>trans</I>-1-Acetyl-4-hydroxy-<SC>L</SC>-proline
A5048012

<I>trans</I>-1-Acetyl-4-hydroxy-<SC>L</SC>-proline , 99% , 33996-33-7

Synonym(s):
N-Acetyl-L-hydroxyproline

CAS NO.:33996-33-7

Empirical Formula: C7H11NO4

Molecular Weight: 173.17

MDL number: MFCD00037339

EINECS: 251-780-6

Pack Size Price Stock Quantity
10G RMB304.00 In Stock
25g RMB564.80 In Stock
50G RMB767.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 132-133 °C (dec.)(lit.)
alpha  -119 º (c=4 in H2O)
Boiling point: 303.8°C (rough estimate)
Density  1.3346 (rough estimate)
vapor pressure  0Pa at 20℃
refractive index  1.4490 (estimate)
storage temp.  Sealed in dry,2-8°C
solubility  DMSO : ≥ 32 mg/mL (184.79 mM)
form  Crystalline Powder
pka 3.48±0.40(Predicted)
color  White
optical activity [α]20/D 119°, c = 4 in H2O
Merck  14,6903
BRN  84043
InChIKey BAPRUDZDYCKSOQ-RITPCOANSA-N
LogP -1.51 at 20℃
CAS DataBase Reference 33996-33-7(CAS DataBase Reference)
EPA Substance Registry System L-Proline, 1-acetyl-4-hydroxy-, (4R)- (33996-33-7)

Description and Uses

trans-1-Acetyl-4-hydroxy-L-proline can be used:

  • In the stereospecific synthesis of 4-fluoroglutamic acid.
  • To synthesize molecular targets for von Hippel-Lindau (VHL) E3 ubiquitin ligase.
  • As a precursor to synthesize pseudopoly(amino acids) such as poly(trans-4-hydroxy-4-acyl-L-proline ester) and a biodegradable polymer, poly(lactic acid-glycolic acid-4-hydroxyproline).

Safety

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  41
Safety Statements  26-36
WGK Germany  3
10
TSCA  Yes
HS Code  29339900

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