A5007356
Amodiaquine , 98% , 86-42-0
CAS NO.:86-42-0
Empirical Formula: C20H22ClN3O
Molecular Weight: 355.86
MDL number: MFCD00552927
EINECS: 201-669-3
Pack Size | Price | Stock | Quantity |
5mg | RMB455.20 | In Stock |
|
10mg | RMB1353.60 | In Stock |
|
25mg | RMB1519.20 | In Stock |
|
50mg | RMB2719.20 | In Stock |
|
100mg | RMB4623.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 208°C |
Boiling point: | 478.0±45.0 °C(Predicted) |
Density | 1.258 |
storage temp. | -20°C Freezer |
solubility | DMSO (Slightly, Sonicated), Methanol (Slightly) |
form | Solid |
pka | 9.43±0.50(Predicted) |
color | Pale Yellow to Light Yellow |
CAS DataBase Reference | 86-42-0(CAS DataBase Reference) |
NIST Chemistry Reference | Amodiaquine(86-42-0) |
Description and Uses
Amodiaquine is a prodrug form of the antimalarial compound N-desethyl amodiaquine . It is active against several strains of P. falciparum in vitro (EC50s = 0.23-0.52 nM) and exhibits a synergistic effect when used in combination with N-desethyl amodiaquine. Amodiaquine dose-dependently inhibits development of parasitemia in a mouse model of P. berghei infection.
An antimalarial
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264-P270-P301+P312-P330-P501 |
Hazardous Substances Data | 86-42-0(Hazardous Substances Data) |
Toxicity | LD50 oral in mouse: 550mg/kg |