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A5007356

Amodiaquine , 98% , 86-42-0

CAS NO.:86-42-0

Empirical Formula: C20H22ClN3O

Molecular Weight: 355.86

MDL number: MFCD00552927

EINECS: 201-669-3

Pack Size Price Stock Quantity
5mg RMB455.20 In Stock
10mg RMB1353.60 In Stock
25mg RMB1519.20 In Stock
50mg RMB2719.20 In Stock
100mg RMB4623.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 208°C
Boiling point: 478.0±45.0 °C(Predicted)
Density  1.258
storage temp.  -20°C Freezer
solubility  DMSO (Slightly, Sonicated), Methanol (Slightly)
form  Solid
pka 9.43±0.50(Predicted)
color  Pale Yellow to Light Yellow
CAS DataBase Reference 86-42-0(CAS DataBase Reference)
NIST Chemistry Reference Amodiaquine(86-42-0)

Description and Uses

Amodiaquine is a prodrug form of the antimalarial compound N-desethyl amodiaquine . It is active against several strains of P. falciparum in vitro (EC50s = 0.23-0.52 nM) and exhibits a synergistic effect when used in combination with N-desethyl amodiaquine. Amodiaquine dose-dependently inhibits development of parasitemia in a mouse model of P. berghei infection.

An antimalarial

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazardous Substances Data 86-42-0(Hazardous Substances Data)
Toxicity LD50 oral in mouse: 550mg/kg

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