A4788212
6-(5H)-Phenanthridinone , ≥98.0%(HPLC) , 1015-89-0
Synonym(s):
NSC 11021;NSC 40943;NSC 61083
CAS NO.：1015-89-0
Empirical Formula: C13H9NO
Molecular Weight: 195.22
MDL number: MFCD00004988
EINECS: 213-804-3
| Pack Size | Price | Stock | Quantity |
| 1G | RMB30.40 | In Stock |
|
| 5G | RMB95.20 | In Stock |
|
| 25G | RMB240.00 | In Stock |
|
| 100g | RMB920.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 290-292 °C(lit.) |
| Boiling point: | 435 °C |
| Density | 1.230±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMF: 1mg/mL; DMF:PBS (pH 7.2) (1:5): 0.16mg/mL |
| form | powder to crystal |
| pka | 13.27±0.20(Predicted) |
| color | White to Light yellow to Light orange |
| Water Solubility | Soluble in DMSO (5 mg/ml). Insoluble in water. |
| λmax | 338nm(EtOH)(lit.) |
| BRN | 140641 |
Description and Uses
6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | SG0370000 |
| HS Code | 29337900 |
