Home Categories Biochemical Engineering 2'-Deoxy-7,8-dihydro-8-oxoguanosine
A4784812

2'-Deoxy-7,8-dihydro-8-oxoguanosine , ≥95.0%(HPLC) , 88847-89-6

Synonym(s):
8-Oxo-7,8-dihydro-2′-deoxyguanosine;8-Oxo-dG

CAS NO.:88847-89-6

Empirical Formula: C10H13N5O5

Molecular Weight: 283.24

MDL number: MFCD00210311

Pack Size Price Stock Quantity
1MG RMB319.20 In Stock
5MG RMB1119.20 In Stock
25mg RMB3199.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 217-220°C
Density  2.25±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Soluble in DMSO (up to 10 mg/ml).
pka 7.86±0.20(Predicted)
form  White to off-white solid.
color  Off-white
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Description and Uses

8-Oxo-2′-deoxyguanosine (88847-89-6) is a useful marker for DNA damage via a variety of oxidative processes.1?It is a critical biomarker for oxidative stress and carcinogenesis.2,3

8-Hydroxy-2′-deoxyguanosine has been used:

  • as a standard to analyse the oxidative DNA damage in the placenta of normal and abnormal pregnancies by electrochemical detection
  • as a standard for high performance liquid chromatography (HPLC) with electrochemical detection (ECD) measurement
  • as a standard for HPLC and as a urinary marker of oxidative stress in order to assess the potential?antioxidant?activity of green coffee bean extract (GCBE) in vivo
  • as a standard for LC/MS/MS analysis

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
RTECS  MF8782675
HS Code  29349990

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