Home Categories Pharmaceutical intermediates 2-Hydroxy-5-methyl-3-nitropyridine
A4749812

2-Hydroxy-5-methyl-3-nitropyridine , 97% , 7464-14-4

CAS NO.:7464-14-4

Empirical Formula: C6H6N2O3

Molecular Weight: 154.12

MDL number: MFCD02070021

Pack Size Price Stock Quantity
1g RMB63.20 In Stock
5G RMB81.60 In Stock
25G RMB284.00 In Stock
50g RMB522.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 179 °C (dec.) (lit.)
Boiling point: 353.3±35.0 °C(Predicted)
Density  1.24 g/mL at 25 °C(lit.)
Flash point: 179 °C
storage temp.  2-8°C
solubility  Dimethylformamide[soluble in]
solubility  soluble in Dimethylformamide
form  powder to crystal
pka 8.78±0.10(Predicted)
color  White to Yellow

Description and Uses

2-Hydroxy-5-methyl-3-nitropyridine (HMPN) is an organosynthetic compound that can be used as a feedstock for the synthesis of other compounds or as a biological inhibitor, such as in the preparation of 2-chloro-5-methyl-3-nitropyridine and transglutaminase 2 (tg2) inhibitors. It reacts with molybdenum and chloride. It is able to react with molybdenum and chloride, and it is able to increase the reaction yield and time. It is also used to explain its reactivity with xylene.

2-Hydroxy-5-methyl-3-nitropyridine may be used in the preparation of 2-chloro-5-methyl-3-nitropyridine via chlorination, using thionyl chloride. It may also be used is preparing proteasome inhibitors containing 5-methylpyridin-2(1H)-one moiety.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Hazard Note  Irritant
HS Code  2933399990

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