Home Categories Pharmaceutical intermediates 4-Hydroxy-2-methylquinoline
A4746512

4-Hydroxy-2-methylquinoline , 98% , 607-67-0

Synonym(s):
2-Methyl-4-quinolinol

CAS NO.:607-67-0

Empirical Formula: C10H9NO

Molecular Weight: 159.18

MDL number: MFCD00006758

EINECS: 210-140-6

Pack Size Price Stock Quantity
5G RMB143.20 In Stock
25G RMB592.80 In Stock
100G RMB2042.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 234-236 °C(lit.)
Boiling point: 284.68°C (rough estimate)
Density  1.1202 (rough estimate)
refractive index  1.6070 (estimate)
storage temp.  Sealed in dry,Room Temperature
form  powder to crystal
pka 4.44±0.40(Predicted)
color  White to Light yellow
Water Solubility  Slightly soluble in water.
λmax 317nm(CHCl3)(lit.)
BRN  118320
LogP 1.902 (est)
CAS DataBase Reference 607-67-0(CAS DataBase Reference)
NIST Chemistry Reference 4-Quinolinol, 2-methyl-(607-67-0)

Description and Uses

4-Hydroxy-2-methylquinoline can be used as an intermediate in the synthesis of a wide range of medicinally important compounds such as:

  • Synthesis of 2-(quinolin-4-yloxy)acetamides as potent antitubercular agents.
  • Synthesis of 2-arylethenylquinoline derivatives for the treatment of Alzheimer′s disease.
  • Synthesis of 1,10-diethoxy-1H-pyrano[4,3-b]quinolones as antibacterial agents.
  • Synthesis of phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phophodiesterase 10A (PDE10A) inhibitors.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-36/37/39-22
WGK Germany  3
HS Code  29334900

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