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A4718912

Hexaconazole , Analysis standard product, 98% , 79983-71-4

Synonym(s):
(±)-2-(2,4-Dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-hexanol

CAS NO.:79983-71-4

Empirical Formula: C14H17Cl2N3O

Molecular Weight: 314.21

MDL number: MFCD00144441

EINECS: 413-050-7

Pack Size Price Stock Quantity
100MG RMB239.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 111°C
Boiling point: 490.3±55.0 °C(Predicted)
Density  d25 1.29
vapor pressure  1.8 x l0-6 Pa (20 °C)
refractive index  1.5490 (estimate)
storage temp.  Inert atmosphere,Room Temperature
solubility  DMSO: Soluble; Methanol: Soluble
form  Solid
Water Solubility  17 mg l-1(20 °C)
pka 12.26±0.29(Predicted)
color  White to off-white
Merck  13,4700
BRN  8328399
InChIKey STMIIPIFODONDC-UHFFFAOYSA-N

Description and Uses

Hexaconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death. It is fungicidal against the powdery mildews B. graminis and S. cucurbitae on cucumber plants in a concentration-dependent manner and is curative against powdery mildew on barley plants when used at a concentration of 6.7 mg/L. It also inhibits growth of R. bataticola and S. rolfsii (ED50s = 6.35 and 1.27 mg/L, respectively). Exogenous application of hexaconazole (15 mg/L) to M. chamomilla plants improves water, proline, and protein contents as well as increases non-enzymatic and enzymatic antioxidant and apigenin-7-glucoside content during a water deficit stress tolerance test. Hexaconazole inhibits the differentiation of mouse embryonic stem cells into cardiomyocytes (EC50 = 16.6 μM). It also induces bone morphological defects in mouse fetuses when administered to pregnant adult females during gestation.

Hexaconazole is a systematic fungicide of the triazole class. Hexaconazole has a broad spectrum antifungal activity and is commonly used in the control of apple, coffee and peanut diseases.

Safety

Symbol(GHS) 
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H317-H411
Precautionary statements  P261-P264-P273-P280-P301+P312-P302+P352
Hazard Codes  Xn;N,N,Xn
Risk Statements  22-43-51/53
Safety Statements  2-24-37-61
RIDADR  UN3077 9/PG 3
WGK Germany  2
RTECS  XZ4803200
Toxicity LD50 orally in mallard ducks, male rats, female rats: >4000, 2189, 6071 mg/kg; dermally in rats: >2000 mg/kg; LC50 (96 hour) in rainbow trout: >6.7 mg/l (Shephard)

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