Home Categories Pharmaceutical intermediates 2-Hydroxy-5-methylpyridine
A4708412

2-Hydroxy-5-methylpyridine , 97% , 1003-68-5

CAS NO.:1003-68-5

Empirical Formula: C6H7NO

Molecular Weight: 109.13

MDL number: MFCD03092888

EINECS: 213-713-9

Pack Size Price Stock Quantity
1G RMB33.60 In Stock
5G RMB67.20 In Stock
25G RMB177.60 In Stock
100G RMB584.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 183-187 °C (lit.)
Boiling point: 304.2±15.0 °C(Predicted)
Density  1.053±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form  Solid
pka 12.43±0.10(Predicted)
color  Pale Yellow to Light Yellow
BRN  107074
InChI InChI=1S/C6H7NO/c1-5-2-3-6(8)7-4-5/h2-4H,1H3,(H,7,8)
InChIKey SOHMZGMHXUQHGE-UHFFFAOYSA-N
SMILES C1(=O)NC=C(C)C=C1
CAS DataBase Reference 1003-68-5(CAS DataBase Reference)
NIST Chemistry Reference 2(1H)-pyridinone, 5-methyl-(1003-68-5)

Description and Uses

2-Hydroxy-5-methylpyridine (cas# 1003-68-5) is a useful compound for organic synthesis. In particular it has been used for the diastereoselective preparation of cyclobutane-fused pyridinyl sulfonyl fluorides. 2-hydroxy-5-methylpyridine and Iodobenzene were the impurities present in Pirfenidone (PFD) drug substance. PFD is a novel antifibrotic agent approved for mild to moderate Idiopathic pulmonary fibrosis (IPF) as orphan drug[1].

Safety

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
Hazard Codes  Xn
Risk Statements  22-37/38-41-36/37/39
Safety Statements  26-36-37
WGK Germany  3
HS Code  29333990

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