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A4696612

8-Hydroxyquinoline , AR,99.0% , 148-24-3

Synonym(s):
8-Hydroxyquinoline;8-Oxychinolin;8-Quinolinol;Oxine;Oxine, 8-Quinolinol

CAS NO.:148-24-3

Empirical Formula: C9H7NO

Molecular Weight: 145.16

MDL number: MFCD00006807

EINECS: 205-711-1

Pack Size Price Stock Quantity
25G RMB29.60 In Stock
100G RMB53.60 In Stock
500G RMB164.00 In Stock
2.5KG RMB648.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 70-73 °C(lit.)
Boiling point: 267 °C752 mm Hg(lit.)
Density  1.0340
vapor pressure  0.221Pa at 25℃
refractive index  1.4500 (estimate)
Flash point: 267°C
storage temp.  Store below +30°C.
solubility  0.56g/l
pka 5.017(at 20℃)
form  Liquid
color  White to pale yellow or light beige
Water Solubility  INSOLUBLE
Sensitive  Light Sensitive
Merck  14,4843
BRN  114512
InChIKey MCJGNVYPOGVAJF-UHFFFAOYSA-N
LogP 1.85 at 25℃
CAS DataBase Reference 148-24-3(CAS DataBase Reference)
IARC 3 (Vol. 13, Sup 7) 1987
NIST Chemistry Reference 8-Quinolinol(148-24-3)
EPA Substance Registry System 8-Quinolinol (148-24-3)

Description and Uses

8-Hydroxyquinoline has a wide variety of uses. Primarily because of their metal chelating properties, 8-hydroxyquinoline and its salts, halogenated derivatives, and metal complexes have been used as analytical reagents (Hollingshead, 1954) and as antimicrobial agents in medicine, fungicides, and insecticides (Harvey, 1975). It is also used as a preservative in cosmetics and tobacco, a chemical intermediate in dye synthesis (IARC, 1977), and a precipitating reagent for uranium and other radioactive metals in nuclear power plant liquid waste effluent. It is used in nuclear medicine with indium-111 (Davis et al., 1978).

Safety

Symbol(GHS) 
GHS05,GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301-H317-H318-H360D-H410
Precautionary statements  P202-P273-P280-P301+P310-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-68-36/37/38
Safety Statements  45-36/37/39-26-36
RIDADR  2811
WGK Germany  3
RTECS  VC4200000
Hazard Note  Harmful/Irritant
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29334990
Hazardous Substances Data 148-24-3(Hazardous Substances Data)
Toxicity An LD50 value of 1,200mg/kg was reported for oral administration of 8-hydroxyquinoline to rats (straidsex unspecified; AAPCO, 1966);a value of 48 mg/kg was reported for intraperitoneal administration to mice (strain/sex unspecxed; Bernstein et al., 1963).

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