18β-Glycyrrhetinic acid , 97% , 471-53-4
Synonym(s):
Enoxolone;18β-Glycyrrhetinic acid;3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid;Glycyrrhetin;Subglycyrrhelinic acid
CAS NO.：471-53-4
Empirical Formula: C30H46O4
Molecular Weight: 470.69
MDL number: MFCD00003706
EINECS: 207-444-6
| Pack Size | Price | Stock | Quantity |
| 1G | RMB51.20 | In Stock |
|
| 5G | RMB81.60 | In Stock |
|
| 25G | RMB274.40 | In Stock |
|
| 100G | RMB873.60 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 292-295 °C(lit.) |
| alpha | 165 º (c=1, CHCl3,on dry ba) |
| Boiling point: | 492.11°C (rough estimate) |
| Density | 0.9967 (rough estimate) |
| vapor pressure | 10-220Pa at 20-50℃ |
| refractive index | 162 ° (C=1, MeOH) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride. |
| pka | pKa 5.56±0.1 (Uncertain) |
| form | Crystalline Powder |
| color | White to off-white |
| optical activity | [α]22/D +170.0°, c = 1 in chloroform |
| Water Solubility | SOLUBLE IN ACETIC ACID |
| Merck | 14,3590 |
| BRN | 2229654 |
| LogP | 4.5 at 20℃ |
Description and Uses
Extracting from liquorice (Glycyrrhiza uralensis Fisch, Gan Cao), glycyrrhetic acid also can be detected in other plants, such as Abrus cantoniensis Hance and Herba Abri fruticulosi. As one of traditional Chinese medicines, liquorice has been applied clinically for a long period. Due to its extensive usage, it plays an extremely important role in traditional Chinese medicine formula mainly as “guide” drug. As is recorded in Shen Nong’s Herbal Classic and later in pharmaceutical monographs, liquorice is able to strengthen bones and muscles and enhance metabolism and detoxification. Also, abnormal symptoms of the body and wound can be improved. Glycyrrhetic acid, the most important and potent ingredient of liquorice, has been recorded in Pharmacopoeia of the People’s Republic of China.
glycyrrhetinic acid is anti-irritant, anti-allergenic, anti-inflammatory, skin-lightening, and smoothing properties are attributed to this ingredient, which is also a carrier. It is the organic compound derived from glycyrrhizic acid or shredded licorice roots.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319-H302 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22-36 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | RK0180000 |
| HS Code | 29189900 |
| Toxicity | mouse,LD50,intraperitoneal,308mg/kg (308mg/kg),Drugs in Japan Vol. -, Pg. 319, 1990. |
