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A4616612

Ginsenoside Rh2 , Analysis of standards,> 98% , 78214-33-2

Synonym(s):
(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranoside;20(S)-Ginsenoside-Rh2

CAS NO.:78214-33-2

Empirical Formula: C36H62O8

Molecular Weight: 622.88

MDL number: MFCD00800712

Pack Size Price Stock Quantity
20MG RMB432.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 139-144 °C
Boiling point: 726.4±60.0 °C(Predicted)
Density  1.19±0.1 g/cm3(Predicted)
storage temp.  Inert atmosphere,2-8°C
solubility  DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
pka 12.91±0.70(Predicted)
form  Solid
color  White
InChIKey CKUVNOCSBYYHIS-IRFFNABBSA-N
LogP 5.620 (est)

Description and Uses

Ginsenoside Rh2 is a steroid glycoside found in plants of the genus Panax that has diverse biological activities. It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg. It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner. In vivo, ginsenoside Rh2 decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma. Ginsenoside Rh2 also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.

20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
Safety Statements  24/25
WGK Germany  3
RTECS  LZ5776539
HS Code  29389090

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