A4598229
Methyllithium solution , 3.1Mindiethoxymethane , 917-54-4
Synonym(s):
Lithium methanide;MeLi
CAS NO.：917-54-4
Empirical Formula: CH3Li
Molecular Weight: 21.98
MDL number: MFCD00008253
EINECS: 213-026-4
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 70-71℃ |
| Boiling point: | 88℃ |
| Density | 0.85 g/mL at 20 °C |
| vapor density | 3 (vs air) |
| Flash point: | 5 °F |
| storage temp. | 2-8°C |
| form | Solution |
| color | Colorless to yellow |
| Specific Gravity | 0.83 |
| Water Solubility | Reacts with water. |
| Sensitive | Air & Moisture Sensitive |
| Hydrolytic Sensitivity | 9: reacts extremely rapidly with atmospheric moisture - may be pyrophoric - glove box or sealed system required |
| BRN | 3587162 |
| Exposure limits | ACGIH: TWA 400 ppm; STEL 500 ppm OSHA: TWA 400 ppm(1200 mg/m3) NIOSH: IDLH 1900 ppm |
| CAS DataBase Reference | 917-54-4(CAS DataBase Reference) |
| EPA Substance Registry System | Lithium, methyl- (917-54-4) |
Description and Uses
There are no significant industrial uses of methyllithium, but it is widely used in the laboratory in Grignard type reactions.
Methyllithium is an organolithium reagent mainly used for deprotonation and as a source of methyl anion. It is a strong base and a strong nucleophile.
Safety
| Symbol(GHS) |       GHS02,GHS05,GHS07,GHS08,GHS09,GHS06 |
| Signal word | Danger |
| Hazard statements | H252-H303-H315-H318-H401-H225-H260-H304-H314-H335-H411-H250-H302-H336-H311 |
| Precautionary statements | P210-P223-P231+P232-P261-P370+P378-P422-P222-P280-P305+P351+P338-P309-P310-P402+P404-P301+P310a-P303+P361+P353-P405-P501a |
| Hazard Codes | F+,C,N,F,Xn,Xi |
| Risk Statements | 12-15-17-22-34-66-67-65-51/53-11-36/37/38-36/38-19-40-36/37-37-14/15 |
| Safety Statements | 16-26-36/37/39-45-43-30-60-62-61-36/37 |
| RIDADR | UN 3399 4.3/PG 1 |
| WGK Germany | 2 |
| F | 10 |
| TSCA | Yes |
| HazardClass | 4.3 |
| PackingGroup | I |
| HS Code | 29319090 |
