Tetramisolehydrochloride , ≥99% , 5086-74-8

Synonym(s):
(±)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride

CAS NO.：5086-74-8

Empirical Formula: C11H13ClN2S

Molecular Weight: 240.75

MDL number: MFCD00005536

EINECS: 225-799-5

PRODUCT Properties

• Melting point: 266-267 °C(lit.)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Methanol (Slightly), Water (Slightly, Heated)
• form: Solid
• color: White to Off-White
• Water Solubility: 200 g/L (20 ºC)
• Merck: 13,5480
• BRN: 4358989
• Stability: Hygroscopic
• InChI: InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H
• InChIKey: LAZPBGZRMVRFKY-UHFFFAOYSA-N
• SMILES: C1N2C(=NC(C2)C2=CC=CC=C2)SC1.[H]Cl
• CAS DataBase Reference: 5086-74-8(CAS DataBase Reference)

Description and Uses

Tetramisole hydrochloride is an inhibitor of alkaline phosphatases, is a high purity antiparasitic. It is suitable for inhibition of various alkaline phosphatase (i.e., liver, kidney, placenta, bone and tumor)(Intestinal alkaline phosphatases are only slightly inhibited.). Tetramisole has biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38-20/21/22
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: NJ5950000
• HS Code: 29349990
• Toxicity: LD50 in mice, rats (mg/kg): 22, 24 i.v.; 84, 130 s.c.; 210, 480 orally (Thienpoint)