A1413912
Butenafine HCl , ≥98%(HPLC) , 101827-46-7
Synonym(s):
Butenafine hydrochloride;Mentax;N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine hydrochloride;N-[[4-(1,1-Dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine hydrochloride
CAS NO.：101827-46-7
Empirical Formula: C23H27N.ClH
Molecular Weight: 353.93
MDL number: MFCD00917064
EINECS: 642-354-4
| Pack Size | Price | Stock | Quantity |
| 1G | RMB111.20 | In Stock |
|
| 5G | RMB251.20 | In Stock |
|
| 25G | RMB734.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 210-214°C |
| storage temp. | room temp |
| solubility | DMSO: ≥10mg/mL |
| form | powder |
| color | white to off-white |
| Merck | 14,1518 |
| InChI | InChI=1S/C23H27N.ClH/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20;/h5-15H,16-17H2,1-4H3;1H |
| InChIKey | LJBSAUIFGPSHCN-UHFFFAOYSA-N |
| SMILES | C12C=CC=CC=1C=CC=C2CN(C)CC1=CC=C(C(C)(C)C)C=C1.Cl |
Description and Uses
Butenafine hydrochloride is a new benzylamine antifungal which appears to block the squalene epoxidation step of sterol synthesis in fungi. Active against a broad spectrum of fungi, butenafine hydrochloride is more effective in a guinea-pig model of tinea pedis than clotrimazole, naftifine and tolnaftate. Its efficacy is partially attributed to its long retention time in the skin.
Butenafine HCl is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
