A4366512
Ferrostatin-1 (Fer-1) , ≥99% , 347174-05-4
Pack Size | Price | Stock | Quantity |
5MG | RMB79.20 | In Stock |
|
25MG | RMB239.20 | In Stock |
|
100MG | RMB559.20 | In Stock |
|
500mg | RMB1599.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 437.3±35.0 °C(Predicted) |
Density | 1.150±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: soluble10mg/mL, clear |
pka | 4.78±0.11(Predicted) |
form | powder |
color | purple to brown |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
InChIKey | UJHBVMHOBZBWMX-UHFFFAOYSA-N |
Description and Uses
Ferrostatin-1 (347174-05-4) inhibits ferroptosis (EC50=60 nM), an iron-dependent form of nonapoptotic cell death.1?Potent inhibitor of ferroptosis in cancer cells and glutamate-induced cell death in organotypic rat brain slices.1?Blocks the cytotoxic effects of sorafenib in hepatocellular carcinoma cells.2?Ferrostatin-1 inhibits oxidative lipid damage and cell death in diverse disease models3 and prevents apoptosis of renal proximal tubular cells induced by reactive oxygen species4.
Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26 |
WGK Germany | 3 |
HazardClass | IRRITANT |
HS Code | 2922498590 |