Home Categories Biochemical Engineering Ferrostatin-1 (Fer-1)
A4366512

Ferrostatin-1 (Fer-1) , ≥99% , 347174-05-4

CAS NO.:347174-05-4

Empirical Formula: C15H22N2O2

Molecular Weight: 262.35

MDL number: MFCD08072959

Pack Size Price Stock Quantity
5MG RMB79.20 In Stock
25MG RMB239.20 In Stock
100MG RMB559.20 In Stock
500mg RMB1599.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 437.3±35.0 °C(Predicted)
Density  1.150±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: soluble10mg/mL, clear
pka 4.78±0.11(Predicted)
form  powder
color  purple to brown
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChIKey UJHBVMHOBZBWMX-UHFFFAOYSA-N

Description and Uses

Ferrostatin-1 (347174-05-4) inhibits ferroptosis (EC50=60 nM), an iron-dependent form of nonapoptotic cell death.1?Potent inhibitor of ferroptosis in cancer cells and glutamate-induced cell death in organotypic rat brain slices.1?Blocks the cytotoxic effects of sorafenib in hepatocellular carcinoma cells.2?Ferrostatin-1 inhibits oxidative lipid damage and cell death in diverse disease models3 and prevents apoptosis of renal proximal tubular cells induced by reactive oxygen species4.

Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
HazardClass  IRRITANT
HS Code  2922498590

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