4-Fluoro-3-hydroxybenzoic acid , 98% , 51446-31-2

CAS NO.：51446-31-2

Empirical Formula: C7H5FO3

Molecular Weight: 156.11

MDL number: MFCD00269641

EINECS: 625-872-5

PRODUCT Properties

• Melting point: 214-218 °C (lit.)
• Boiling point: 324.0±27.0 °C(Predicted)
• Density: 1.492±0.06 g/cm3(Predicted)
• storage temp.: Inert atmosphere,Room Temperature
• pka: 4.02±0.10(Predicted)
• form: Powder or Crystalline Powder
• color: White to pale brown
• BRN: 2829723
• CAS DataBase Reference: 51446-31-2(CAS DataBase Reference)

Description and Uses

4-Fluoro-3-hydroxybenzoic acid may serve as a starting material in the synthesis of the following potent inhibitors of β-arylsulfotransferase IV (β-AST-IV):

• 6-(2-(N-4-fluoro-3-hydroxybenzoylamino)ethylamino)purine via reaction with O-benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate(HBTU) and 6-((2-ammonium trifluroacetate)ethylamino)purine
• 6-(12-(N-4-fluoro-3-hydroxybenzoylamino)dodecylamino)purine via reaction with O-benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate(HBTU) and 6-((12-ammonium trifluroacetate)dodecylamino)purine
• 6-(12-(N-4-fluoro-3-hydroxybenzoylamino)dodecylamino)purine via reaction with O-benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate(HBTU) and 6-((12-ammonium trifluroacetate)dodecylamino)purine
• 2-chloro-6-(12-(N-4-fluoro-3-hydroxybenzoylamino)dodecylamino)purine via reaction with O-benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate(HBTU) and 2-chloro-6-((12-ammonium trifluroacetate)dodecylamino)purine
• 12-N-boc-1-N-(4-fluoro-3-hydroxybenzoyl)diaminododecane via reaction with O-benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate(HBTU) and N-boc-1,12-diaminododecane

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi,C
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazard Note: Corrosive
• HazardClass: IRRITANT
• HS Code: 2918290090