1-Formylpiperidine , 99% , 2591-86-8

Synonym(s):
N-Carbaldehyde piperidine;NFP;Piperidine-1-carboxaldehyde

CAS NO.：2591-86-8

Empirical Formula: C6H11NO

Molecular Weight: 113.16

MDL number: MFCD00006483

EINECS: 219-986-0

PRODUCT Properties

• Melting point: -31 °C
• Boiling point: 222 °C(lit.)
• Density: 1.019 g/mL at 25 °C(lit.)
• vapor pressure: 0.1 mm Hg ( 25 °C)
• refractive index: n20/D 1.484(lit.)
• Flash point: 197 °F
• storage temp.: Store below +30°C.
• form: Liquid
• pka: -0.44±0.20(Predicted)
• Specific Gravity: 1.02
• color: Clear colorless to slightly yellow
• Water Solubility: freely soluble
• BRN: 107697
• Dielectric constant: 26.149999999999999

Description and Uses

This simple piperidine base has recently been discovered in the oxygenated fraction from Piper nigrum. The structure has been elucidated from chemical and spectroscopic data.

Reactant for:

• Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoate
• Vilsmeier-type reactions of pyrazoles with amides in the presence of phosphorous oxychloride
• CO-free aminocarbonylation of N-substituted formamides with aryl iodides/bromides catalyzed by palladium acetate and Xantphos for synthesis of arylamides
• Synthesis of alternating copolymers for organic photovoltaic applications
• One-pot double functionalization of π-deficient heterocyclic lithium reagents
• Synthesis of thermally stable piezofluorochromic aggregation-induced emission compounds

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H302-H311-H319
• Precautionary statements: P264-P270-P280-P301+P312-P302+P352+P312-P305+P351+P338
• Hazard Codes: Xn,Xi
• Risk Statements: 21/22-36/37/38
• Safety Statements: 26-36/37-36
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 3
• RTECS: TN0380000
• TSCA: Yes
• HazardClass: 6.1(b)
• PackingGroup: III
• HS Code: 29333999