1-Formylpiperidine , 99% , 2591-86-8

Synonym(s):
N-Carbaldehyde piperidine;NFP;Piperidine-1-carboxaldehyde

CAS NO.：2591-86-8

Empirical Formula: C6H11NO

Molecular Weight: 113.16

MDL number: MFCD00006483

EINECS: 219-986-0

PRODUCT Properties

• Melting point: -31 °C
• Boiling point: 222 °C(lit.)
• Density: 1.019 g/mL at 25 °C(lit.)
• vapor pressure: 0.1 mm Hg ( 25 °C)
• refractive index: n20/D 1.484(lit.)
• Flash point: 197 °F
• storage temp.: Store below +30°C.
• form: Liquid
• pka: -0.44±0.20(Predicted)
• Specific Gravity: 1.02
• color: Clear colorless to slightly yellow
• Water Solubility: freely soluble
• BRN: 107697
• Dielectric constant: 26.149999999999999
• CAS DataBase Reference: 2591-86-8(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxaldehyde(2591-86-8)
• EPA Substance Registry System: N-Formylpiperidine (2591-86-8)

Description and Uses

This simple piperidine base has recently been discovered in the oxygenated fraction from Piper nigrum. The structure has been elucidated from chemical and spectroscopic data.

Reactant for:

• Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoate
• Vilsmeier-type reactions of pyrazoles with amides in the presence of phosphorous oxychloride
• CO-free aminocarbonylation of N-substituted formamides with aryl iodides/bromides catalyzed by palladium acetate and Xantphos for synthesis of arylamides
• Synthesis of alternating copolymers for organic photovoltaic applications
• One-pot double functionalization of π-deficient heterocyclic lithium reagents
• Synthesis of thermally stable piezofluorochromic aggregation-induced emission compounds

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H302-H311-H319
• Precautionary statements: P264-P270-P280-P301+P312-P302+P352+P312-P305+P351+P338
• Hazard Codes: Xn,Xi
• Risk Statements: 21/22-36/37/38
• Safety Statements: 26-36/37-36
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 3
• RTECS: TN0380000
• TSCA: Yes
• HazardClass: 6.1(b)
• PackingGroup: III
• HS Code: 29333999