Home Categories Biochemical Engineering Fmoc-Leu-OH
A4277212

Fmoc-Leu-OH , 98% , 35661-60-0

Synonym(s):
N-(9-Fluorenylmethoxycarbonyl)-L-leucine;Fmoc-L-leucine;Fmoc-Leu-OH;N-α-Fmoc-L-leucine

CAS NO.:35661-60-0

Empirical Formula: C21H23NO4

Molecular Weight: 353.41

MDL number: MFCD00037133

EINECS: 252-662-7

Pack Size Price Stock Quantity
5G RMB24.00 In Stock
25G RMB74.40 In Stock
100G RMB203.20 In Stock
500g RMB1012.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 152-156 °C(lit.)
alpha  -26 º (c=1,DMF 24 ºC)
Boiling point: 486.83°C (rough estimate)
Density  1.2107 (rough estimate)
refractive index  -25 ° (C=1, DMF)
storage temp.  Store below +30°C.
solubility  DMF (Slightly), DMSO (Slightly)
pka 3.91±0.21(Predicted)
form  Solid
color  White to Off-White
optical activity [α]20/D 25±2°, c = 1% in DMF
BRN  2178254
Stability: Hygroscopic
InChIKey CBPJQFCAFFNICX-IBGZPJMESA-N
CAS DataBase Reference 35661-60-0(CAS DataBase Reference)

Description and Uses

Fmoc-Leu-OH is isomeric with Fmoc-Ile-OH. Like isoleucine, leucine has branching in the sidechain. The branching is at the gamma carbon instead of the beta carbon as in isoleucine. It is used in chemical and peptide syntheses.

Fmoc-L-Leu-OH, is an amino acid derivative, used in peptide chemistry. It is also one of the novel PPARγ ligands that can activate PPARγ in different ways, that reduces osteoclasts differentiation, and thus are better therapeutic targets in diabetes than traditional antidiabetic drugs.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36/37/39-27-26
WGK Germany  3
HS Code  2924 29 70

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