Fmoc-Val-OH , 98% , 68858-20-8

Synonym(s):
N-(9-Fluorenylmethoxycarbonyl)-L-valine;Fmoc-L-valine;Fmoc-Val-OH;N-α-Fmoc-L-valine

CAS NO.：68858-20-8

Empirical Formula: C20H21NO4

Molecular Weight: 339.39

MDL number: MFCD00037124

EINECS: 272-515-0

PRODUCT Properties

• Melting point: 143-145 °C(lit.)
• alpha: -16 º (c=1,DMF)
• Boiling point: 475.36°C (rough estimate)
• Density: 1.2270 (rough estimate)
• refractive index: -17.5 ° (C=1, DMF)
• storage temp.: 2-8°C
• solubility: Solubility in methanol gives very faint turbidity.
• pka: 3.90±0.10(Predicted)
• form: Solid
• color: Off-White
• optical activity: [α]20/D 17±1°, c = 1% in DMF
• BRN: 2177443
• InChI: InChI=1S/C20H21NO4/c1-12(2)18(19(22)23)21-20(24)25-11-17-15-9-5-3-7-13(15)14-8-4-6-10-16(14)17/h3-10,12,17-18H,11H2,1-2H3,(H,21,24)(H,22,23)/t18-/m0/s1
• InChIKey: UGNIYGNGCNXHTR-SFHVURJKSA-N
• SMILES: C(O)(=O)[C@H](C(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
• CAS DataBase Reference: 68858-20-8(CAS DataBase Reference)

Description and Uses

Fmoc-Val-OH is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Fmoc-valine (in addition to the other amino acids) is commonly used to synthesize 4-thiazolidinones (e.g. (E)-5-(4-Ethylbenzylidene)-2-thioxothiazolidin-4-one [E925745]) and 4-metathiazanones as well.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 36/37/39-26-22-27-24/25
• WGK Germany: 3
• Hazard Note: Irritant
• HS Code: 29242990