0 , 95% , 189028-95-3

CAS NO.：189028-95-3

Empirical Formula: C20H20FNO4

Molecular Weight: 357.38

MDL number: MFCD13194798

EINECS: 606-165-0

PRODUCT Properties

• Boiling point: 572.7±50.0 °C(Predicted)
• Density: 1.297
• storage temp.: 2-8°C
• solubility: Chloroform (Sparingly), Methanol (Slightly)
• form: Solid
• pka: 14.17±0.20(Predicted)
• color: White to Off-White

Description and Uses

(4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1, 3-OXAZOLIDIN-2-ONE is a derivative of 2-oxazolidine, which is an effective antimicrobial. It can be used as a pharmaceutical intermediate for the preparation of ezetimibe which is a drug used to lower the patients’ plasma cholesterol levels.

3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one is an intermediate of Ezetimibe (E975000, E975002), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.