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A3966712

β-Estradiol , 99%, for cell culture , 50-28-2

Synonym(s):
β-Estradiol;17β-Estradiol;17β-Estradiol - CAS 50-28-2 - Calbiochem;3,17β-Dihydroxy-1,3,5(10)-estratriene;Dihydrofolliculin

CAS NO.:50-28-2

Empirical Formula: C18H24O2

Molecular Weight: 272.39

MDL number: MFCD01074033

EINECS: 200-023-8

Pack Size Price Stock Quantity
1G RMB263.20 In Stock
5G RMB959.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 178-179 °C(lit.)
Boiling point: 355.44°C (rough estimate)
alpha  D25 +76 to +83° (dioxane)
Density  1.0708 (rough estimate)
refractive index  80.4 ° (C=1, Dioxane)
Flash point: 2℃
storage temp.  room temp
solubility  Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
form  powder
pka pKa 10.71±0.02(H2O(0.1% p-dioxane) t=25±0.1 I=0.03(KCl))(Approximate)
color  White to off-white
Water Solubility  Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Merck  14,3703
BRN  1914275
BCS Class 1
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey VOXZDWNPVJITMN-ZBRFXRBCSA-N

Description and Uses

Estradiol, 17-beta- is an odorless white to yellow crystalline substance. Molecular weight = 272.42;Boiling point = (decomposes); Freezing/Meltingpoint = 173 - 179℃. Hazard Identification (based onNFPA-704 M Rating System): Health 2, Flammability 1,Reactivity 0. Insoluble in water.

17β-Estradiol is the major estrogen secreted by the premenopausal ovary.This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.

Safety

Symbol(GHS) 
GHS08,GHS09
Signal word  Danger
Hazard statements  H351-H360FD-H362-H410
Precautionary statements  P202-P260-P263-P264-P273-P308+P313
Hazard Codes  T,Xn,F
Risk Statements  60-61-45-63-64-40-36-20/21/22-11-48
Safety Statements  53-22-36/37/39-45-36/37-26-16-36-20
RIDADR  2811
WGK Germany  3
RTECS  KG2975000
8-10
HazardClass  6.1
PackingGroup  III
HS Code  29372390
Toxicity LD50 subcutaneous in rat: > 300mg/kg

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