(-)-Epigallocatechin gallate , 98% , 989-51-5

Synonym(s):
EGCG;(?)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate;(?)-cis-3,3′,4′,5,5′,7-Hexahydroxy-flavane-3-gallate;(?)-Epigallocatechin gallate

CAS NO.：989-51-5

Empirical Formula: C22H18O11

Molecular Weight: 458.37

MDL number: MFCD00075940

EINECS: 479-560-7

PRODUCT Properties

• Melting point: 222-224°C
• alpha: D -185 ±2°(ethanol)
• refractive index: -175.5 ° (C=1, EtOH)
• storage temp.: 2-8°C
• solubility: H2O: ≥5mg/mL, clear
• form: Solid
• Boiling point: 909.1±65.0 °C(Predicted)
• Density: 1.90±0.1 g/cm3(Predicted)
• pka: 7.75±0.25(Predicted)
• color: White to Light Brown
• Water Solubility: Soluble in ethanol, dimethyl formamide, water.
• Merck: 14,3526
• Stability: Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
• InChIKey: WMBWREPUVVBILR-WIYYLYMNSA-N
• LogP: 0.639 (est)

Description and Uses

(-)-Epigallocatechin Gallate is a tumor-inhibiting constituent of green tea. (-)-Epigallocatechin Gallate alters the cleavage of amyloid precursor protein, decreasing production of amaloid-β and amaloid plaques in mice. This compound has neuroprotective properties.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H302-H317-H319-H411
• Precautionary statements: P261-P273-P280-P301+P312-P302+P352-P305+P351+P338
• Safety Statements: 24/25
• WGK Germany: 2
• RTECS: KB5200000
• F: 10-23
• HS Code: 29339900
• Toxicity: LD50 oral in mouse: 2170mg/kg