N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride , 98% , 25952-53-8

Synonym(s):
EDC hydrochloride;EDC;EDAC;WSC hydrochloride;N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride

CAS NO.：25952-53-8

Empirical Formula: C8H18ClN3

Molecular Weight: 191.7

MDL number: MFCD00044916

EINECS: 247-361-2

PRODUCT Properties

• Melting point: 110-115 °C(lit.)
• Density: 0.877 g/mL at 20 °C(lit.)
• vapor pressure: 0.002Pa at 20℃
• refractive index: n20/D 1.461
• storage temp.: -20°C
• solubility: H2O: soluble1 gm/10 ml, clear to very slightly hazy, colorless to very faintly yellow
• form: Crystalline Powder
• color: White to off-white
• Water Solubility: Soluble
• Sensitive: Hygroscopic
• BRN: 5764110
• Stability: Stable, but sensitive to moisture. Incompatible with strong acids, strong oxidizing agents, moisture.
• InChIKey: FPQQSJJWHUJYPU-UHFFFAOYSA-N
• LogP: -2.98 at 25℃
• CAS DataBase Reference: 25952-53-8(CAS DataBase Reference)
• EPA Substance Registry System: 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride (25952-53-8)

Description and Uses

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

Safety

• Symbol(GHS): GHS06,GHS08,GHS09
• Signal word: Danger
• Hazard statements: H302-H311-H315-H317-H373-H410
• Precautionary statements: P260-P273-P280-P301+P312-P302+P352+P312-P314
• Hazard Codes: C,Xi
• Risk Statements: 34-36/37/38-41-37/38-20/21/22
• Safety Statements: 26-36/37/39-45-37/39-36
• RIDADR: UN 2735 8/PG 3
• WGK Germany: 3
• RTECS: FF2200000
• F: 1-3-10
• Hazard Note: Irritant
• TSCA: Y
• HS Code: 29252000
• Toxicity: LD50 intravenous in mouse: 56mg/kg