Home Categories Biochemical Engineering 5′-Deoxy-5′-(methylthio)adenosine
A3664912

5′-Deoxy-5′-(methylthio)adenosine , 95% , 2457-80-9

Synonym(s):
5ʹ-Deoxy-5ʹ-methylthioadenosine - CAS 2457-80-9 - Calbiochem;Methylthioadenosine;MTA;MTA, MeSAdo

CAS NO.:2457-80-9

Empirical Formula: C11H15N5O3S

Molecular Weight: 297.33

MDL number: MFCD00010533

Pack Size Price Stock Quantity
25MG RMB183.20 In Stock
100MG RMB511.20 In Stock
250MG RMB919.20 In Stock
1G RMB2559.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 210-213 °C (dec.)
Boiling point: 642.7±65.0 °C(Predicted)
Density  1.85±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMF (Sparingly), DMSO (Slightly), Methanol (Slightly)
pka 13.10±0.70(Predicted)
form  White solid
color  White to Off-White
BRN  42420

Description and Uses

5′-Deoxy-5′-(methylthio)adenosine has been used as a protein methylation inhibitor to reduce E2F transcription factor 1 (E2F1) protein abundance in hepatocellular carcinoma (HCC) cells. It has also been used to inhibit histone methylation modification and study its role in hypoxia inducible factor-1 (Hif-1) nuclear transport.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Safety Statements  22-24/25
WGK Germany  3
RTECS  AU7410000
10-21

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